Expression of 1,25-Dihydroxy Vitamin D3 Receptor in Breast Carcinoma
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چکیده
منابع مشابه
Effect of 1,25-dihydroxy-vitamin D3 in experimental sepsis
BACKGROUND In addition to the regulation of calcium homeostasis, vitamin D affects the cellular immune system, targets the TNF-alpha pathway and increases vasoconstrictor response to angiotensin II. We therefore examined the effect of 1,25-dihydroxy-vitamin D(3) on coagulation and organ failure in experimental sepsis in the rat. METHODS Three series of placebo-controlled studies were conducte...
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We studied the effect of 1,25-dihydroxy vitamin D3 [1,25(OH)2D3] on toll-like receptor (TLR) gene expression in neutrophils cultured with Mycobacterium tuberculosis (Mtb) with or without 1,25(OH)2D3 in pulmonary tuberculosis patients and healthy controls. 1,25(OH)2D3 significantly increased the expression of TLR2, TLR9 and TIRAP genes compared to control cells in both the study groups (P < 0.05...
متن کاملIn vitro cellular muscle calcium metabolism. Characterization of effects of 1,25-dihydroxy-vitamin D3 and 25-hydroxy-vitamin D3.
Cultures of vitamin D-deficient chick soleus muscle and 12 day-old chick embryo myoblasts were used to characterize the effects of 1,25-dihydroxy-vitamin D3 and 25-hydroxy-vitamin D3 on muscle cell Ca metabolism. Physiological amounts of both sterols increased the rate and extent of 45Ca uptake by cultures. However, 1,25(OH)2D3 was significantly more effective than 25 OHD3. The greater potency ...
متن کاملMaspin Gene Expression in Invasive Ductal Carcinoma of Breast
Background: The breast cancer is the most prevalent cancer among women, on the other hand absence of myoepithelial cells play a pivotal role in pathogenesis of this cancer. Thus we aimed to investigate the possible abilities of the molecular assay technique to find a relationship between mammary serine protease inhibitor (Maspin) gene expression possibly secreted by my...
متن کاملUpregulation of Endothelin-1/Endothelin A Receptor Expression Correlates with Heparanase Expression in Ovarian Carcinoma
Background: Heparanase and endothelin-1/endothelin A receptor (ET-1/ETAR) expressions increase in cancer. This condition enhances tumor progression and correlates with poor survival. Limited data are documented regarding the role of heparanase and ET-1/ETAR in epithelial ovarian cancer (EOC). We sought to characterize the correlation between heparanase and ET-1/ETAR in EOC.Methods: Thirty patie...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 1998
ISSN: 0022-1554,1551-5044
DOI: 10.1177/002215549804601114